Efficiance of radioiodine remnant ablation in cases of locally differentiated thyroid cancer

On the territory of Russia has increased thyroid cancer after Chernobyl NPP incidence at 1986, and currently accounts for up to 14,000 newly identified cases. Postoperative radioiodine (RAI) remnant ablation is second stage combine treatment differentiated cancer, except prevalence pT 1 N 0 M , with minimal level TG AT-TG, according international guidelines. In past 20 years a significant number published practice guidelines this disease. However, discussion amount medication administration activity (GBq) 131 I, required successful remnants. The study analyzed 353 clinical cases radical surgical DTC. our study, effectiveness radioiodablation was compared certain indicators specific therapeutic I (MBq/kg), in groups patients different levels TSH stimulation (less than 30 mME/ml, more mME/ml). We evaluated absorbed dose residual tissue volume determined by US when administering empirical activity. control WBS carried out 6 months. average eղciency RAI 85.5 %, there were no differences mME/ml 4-30 (p > 0.05). If not detected US, effective range 30-40 MBq/ kg against background TTG greater 4 ՏME/ml strict adherence 14-day low iodine diet. Direct radiometry followed neck scintigraphy (1200 kBq I) calculation recommended determining plan TAD = 300 Gy reduce risk radiation sialoadenitis. At time RAI, 3.9 % had previously undetectable X-rays lung metastases stimulated 124 ng/mL SPECT/CT.